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Centrophenoxine (meclofenoxate hydrochloride) is a substance designed as an ester of dimethylethanolamine (DMAE) and synthetic para-chlorophenoxyacetic acid (pCPA) by scientists from the French National Center for Scientific Research. It was intended to be used in the treatment of Alzheimer’s disease. Currently, it is as a dietary supplement in many countries and commonly used as a nootropic agent.

The exact mechanism of action of centrophenoxine still remains a mystery. Scientists agree that the substance easily crosses the blood-brain barrier, consequently increasing acetylcholine levels in synaptic vesicles. Furthermore, it boosts cerebral circulation, thereby increasing the supply of oxygen and nutrients to the brain and speeding up the elimination of toxins. In addition, it is believed to have antioxidant properties.

Centrophenoxine is also used to improve memory and cognitive functions. It has been observed to significantly increase mental performance, promote focus, speed up thought processes and aid learning. It also boosts energy and motivation levels in many individuals.

Dosage: No Recommended Dietary Allowance was set.

The most common daily dosage is from 200 to 500 mg.

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