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3,4-divanillyltetrahydrofuran is a substance received from nettle root, with the specific ability of reducing the levels of globulin, which is binding the sex hormone (SHBG) and 5-alpha-reductase that contribute to reduce the level of DHT and estrogen. It affects the level of anabolic testosterone. Lowering estrogen levels and maintaining a high level of testosterone, it affects the development of strain ability (strength and endurance) and body composition that improves male silhouette. It is a substance useful in sports supplementation for athletes practising strength athletics. It is a part of the pro-testosterone supplements and herbal mixtures.